BDNF gene expression association with suicide and psychiatric disorders in children and adolescents (Relationship between BDNF gene expression and suicide)
 
Yazarlar (8)
Rabia Yılmaz Kilis State Hospital, Türkiye
Didem Behice Öztop Ankara Üniversitesi, Türkiye
Elif Funda Şener Erciyes Üniversitesi, Türkiye
Merve Çıkılı Uytun Ankara Üniversitesi, Türkiye
Fatma Dal
Kilis State Hospital, Türkiye
Emrah Yıldız Kilis State Hospital, Türkiye
Doç. Dr. Musa ŞAHPOLAT Kilis State Hospital, Türkiye
Gökmen Zararsız Erciyes Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Behavioural Brain Research (Q3)
Dergi ISSN 0166-4328 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 07-2021
Cilt / Sayı / Sayfa 410 / 1 / 1–7 DOI 10.1016/j.bbr.2021.113350
Makale Linki https://pubmed.ncbi.nlm.nih.gov/33971247/
Özet
ObjectiveIn the current study, it was aimed to investigate the relationship between BDNF gene expression and childhood suicide attempt, childhood traumatic experiences, and problem-solving skills in children and adolescents.MethodsThe suicide group consisted of 100 children and adolescents aged 11–18 years who were referred to our outpatient department due to suicide attempt. For further comparisons, 100 children and adolescents who have no any psychiatric diagnosis were referred to our same outpatient department were selected. A sociodemographic data form, the Schedule for Affective Disorders and Schizophrenia for School-Age Children- Present and Lifetime version (K-SADS-PL), the Suicide Intent Scale (SIS), Problem Solving Inventory (PSI), and the Childhood Trauma Questionnaire (CTQ) were used for both groups. Total RNA was isolated from whole blood samples and BDNF gene expression …
Anahtar Kelimeler
Adolescent | BDNF | Child | Gene expression | Suicide | Trauma