| Makale Türü |
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| Dergi Adı | Journal of Affective Disorders Reports | ||
| Dergi ISSN | 2666-9153 Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-12-2022 |
| Cilt / Sayı / Sayfa | 10 / 1 / 1–9 | DOI | 10.1016/j.jadr.2022.100406 |
| Makale Linki | http://dx.doi.org/10.1016/j.jadr.2022.100406 | ||
| UAK Araştırma Alanları |
Ruh Sağlığı ve Hastalıkları
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| Özet |
| BackgroundSeveral lines of evidence indicate that circadian rhythm disruption is associated with bipolar disorder (BPD). This strong association, along with evidence from genome wide association studies (GWAS) implicating clock and clock controlled genes with BDP and efficacy of lithium treatment, suggests that BPD circadian rhythm disruption may represent a core etiology feature. Lower morning expression of the neuropeptide somatostatin (SST) has been previously reported in the brain and cerebral spinal fluid of subjects with BPD, coinciding with increased morning severity of anxiety and depression. We aimed to test the hypothesis that levels of neuropeptides involved in circadian rhythm regulation, including somatostatin (SST), neuropeptide-Y (NPY), arginine vasopressin (AVP), vasoactive intestinal peptide (VIP) and cortisol levels, are altered in blood samples collected in the morning from patients BPD … |
| Anahtar Kelimeler |
| Anxiety | Anxiety/anxiety disorders | Bipolar disorder | Circadian rhythm | Depression | Neuropeptide | Sleep disorders |
| Atıf Sayıları | |
| Scopus | 1 |
| Google Scholar | 1 |
| Dergi Adı | Journal of Affective Disorders Reports |
| Yayıncı | Elsevier B.V. |
| Açık Erişim | Evet |
| E-ISSN | 2666-9153 |
| CiteScore | 4,9 |
| SJR | 0,904 |
| SNIP | 0,822 |