Plasma nesfatin 1 level in patients with first attack psychosis
Yazarlar (4)
Doç. Dr. Musa ŞAHPOLAT Kilis State Hospital, Türkiye
Doç. Dr. Musa ŞAHPOLAT Kilis State Hospital, Türkiye
M. Ari
Mustafa Kemal Üniversitesi, Türkiye
Mustafa Kemal Üniversitesi, Türkiye
M. Ari
Mustafa Kemal Üniversitesi, Türkiye
Mustafa Kemal Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Bratislava Medical Journal | ||
| Dergi ISSN | 0006-9248 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2017 |
| Cilt / Sayı / Sayfa | 118 / 2 / 77–79 | DOI | 10.4149/BLL_2017_015 |
| Makale Linki | http://dx.doi.org/10.4149/bll_2017_015 | ||
| Özet |
| OBJECTIVES This study aimed to investigate the possible relationship between plasma concentrations of nesfatin 1 and first attack psychosis. METHODS Totally, 32 patients with the first episode psychosis and 33 randomly selected weight- and body mass index-matched healthy volunteers admitted to Mustafa Kemal University, Faculty of Medicine, Training and Research Hospital, Psychiatry outpatient clinic were included. Healthy control subjects were matched in terms of weight and body mass index (BMI). The Positive and Negative Syndrome Scale (PANNS) was applied to the patient group. The enzyme-linked immunosorbent assay (ELISA) method was used to measure plasma nesfatin 1 levels. RESULTS The mean nesfatin 1 level was lower in the patients with the first attack psychosis (0.60 ± 1.00 ng/mL) than in the control group (0.75 ± 1.07 ng/mL).However it did not reach statistical significance (t = -0.567, p = 0.573). There was no statistically significant correlation between plasma nesfatin 1 levels and total PANNS scores in the patient group (r = -0.262, p = 0.148). CONCLUSION Our study was the first to investigate the nesfatin 1 levels in patients with the first episode psychosis. Based on our study results, nesfatin 1 might be related to some central nervous system pathologies, including the severity of a psychiatric disorder; however, further large-scale studies are required to establish a conclusion. |
| Anahtar Kelimeler |
| Body mass index | First attack psychosis | Plasma nesfatin 1 |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 11 |
| Web of Science | 7 |
| Scopus | 11 |