Lyophilized nano-liposomal system for red onion (Allium cepa L.) peel anthocyanin: Characterization, bioaccessibility and release kinetics     
Yazarlar (6)
Doç. Dr. Oya Irmak CEBECİ Yalova Üniversitesi, Türkiye
Ayse Neslihan Dundar
Bursa Teknik Üniversitesi, Türkiye
Kubra Uzuner
Bursa Teknik Üniversitesi, Türkiye
Mahmud Ekrem Parlak
Bursa Teknik Üniversitesi, Türkiye
Adnan Fatih Dagdelen
Bursa Teknik Üniversitesi, Türkiye
Furkan Turker Saricaoglu
Bursa Teknik Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Food Bioscience
Dergi ISSN 2212-4292 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q1
Makale Dili Türkçe
Basım Tarihi 01-2023
Cilt No 53
Sayı 1
Sayfalar 8 / 0
DOI Numarası 10.1016/j.fbio.2023.102702
Makale Linki http://dx.doi.org/10.1016/j.fbio.2023.102702
Özet
In recent years, there has been extensive research on valorization of food wastes and a growing interest in nano-liposomal systems for food applications. This paper discusses the case of phosphatidylcholine basednanophytosomes loaded with anthocyanins extracted from red onion (RNPs) to overcome the bio-stability during digestion. The characterization of lyophilized RNPs in terms of entrapment efficiency, particle size, poly-dispersity index (PDI), ζ-potential, morphological properties, in vitro bioaccessibility and release kinetics were investigated. Entrapment efficiency was determined as 78.63% with lowest particle size (177.73 nm) and PDI value (0.45) and non-dense spherical microstructure for RNP6 (red onion peel anthocyanin extract: soybean phosphatidylcholine at 1:6 ratio). Apart from the particle size, entrapment efficiency was determined higher than 75%, which indicates good entrapment. Additionally, from the cumulative release of RNPs concluded as a successful nano-structure with a two-fold increase in intestinal medium. However, poor Carr index and Hausner ratio suggest some limitations of the current nanoliposomes process which could be further improved. Red onion peel wastes, which are typically discarded, can serve as excellent sources of anthocyanins, and its preparation to nanophytosomes could be used as functional food ingredient or food supplements.
Anahtar Kelimeler
Anthocyanin | Red onion peel | Phytosome | Nanocarrier | Bioactive compounds | In vitro bioaccessibility