Nanophytosomes as a protection system to improve the gastrointestinal stability and bioavailability of phycocyanin
Yazarlar (7)
Doç. Dr. Oya Irmak CEBECİ
Yalova Üniversitesi, Türkiye
Ayse Neslihan Dundar
Bursa Teknik Üniversitesi, Türkiye
Sebahat Ozdemir
Bursa Teknik Üniversitesi, Türkiye
Kubra Uzuner
Bursa Teknik Üniversitesi, Türkiye
Mahmud Ekrem Parlak
Bursa Teknik Üniversitesi, Türkiye
Adnan Fatih Dagdelen
Bursa Teknik Üniversitesi, Türkiye
Furkan Turker Saricaoglu
Bursa Teknik Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Food Bioscience (Q1) | ||
| Dergi ISSN | 2212-4292 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Cilt / Sayı / Sayfa | 50 / 1 / – | DOI | 10.1016/j.fbio.2022.102052 |
| Özet |
| Nano-phytosomes (NP), lipid-based nano-carriers, were used to encapsulate the phycocyanin. Phycocyanin (Phy) is known for its important biological properties with low bioavailability and low stability. The aim of the study was to prepare phosphatidylcholine (PC) based Phy loaded NP to overcome the bioavailability and storage stability issues. The characterization of NP such as entrapment efficiency (EE), particle size, poly-dispersity index (PDI), ζ-potential and microstructural properties was conducted and in vitro bioaccessibility and storage stability of bioactive properties were investigated. The highest EE was determined as 81.92% however with a loading capacity (LC) of 58.12%. Phy-NPs showed good characteristics, such as low PDI values (<0.5), low particle size (106.13–134.10 nm), and non-dense spherical shape of microstructure. All NP complexes showed significant bioaccessibility with total phenolic content (TPC) values greater than 50% in intestinal tract. Unfortunately, PC based NP did not show a clear-cut pattern of TPC and color protection of Phy via increased PC content. |
| Anahtar Kelimeler |
| Phycocyanin | Phytosome | Phytochemical | Nanocarrier | Stability | In vitro bioaccessibility |
Science Direct
Nanophytosomes as a protection system to improve the gastrointestinal stability and bioavailability of phycocyanin
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 23 |
| SCOPUS | 28 |
| Google Scholar | 33 |
| ResearchGate | 29 |