Characterization of pomegranate peel extract loaded nanophytosomes and the enhancement of bio-accessibility and storage stability
      
Yazarlar (7)
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Food Chemistry (Q1)
Dergi ISSN 0308-8146 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 01-2023
Cilt / Sayı / Sayfa 398 / 1 / – DOI 10.1016/j.foodchem.2022.133921
Makale Linki http://dx.doi.org/10.1016/j.foodchem.2022.133921
Özet
Nano-phytosomes are lipid-based nano-carriers and rapidly growing technology for products containing phytochemicals. In this study, pomegranate peel extract (PPE) loaded nanophytosomes (NP) were prepared with phosphatidylcholine (PC) based on thin layer hydration method. The characterization of NP such as entrapment efficiency (EE), particle size, poly-dispersity index (PDI), ζ-potential and microstructural properties was studied and in vitro bioaccessibility and storage stability of bioactive properties were investigated. The highest EE was determined as 94.99 %, indicating a unique ability as nano-carrier. PPE-loaded NPs showed good characteristics, such as lower PDI values (<0.5), lower particle size (166.70-144.40 nm), and spherical shape of microstructure. All NP complexes showed significant bioaccessibility with TPC, CUPRAC, and ABTS values >50 % in the intestinal medium. The lowest TPC and color difference (ΔE) during 28 days of storage were found at 4 °C, although all NP samples showed better stability at all storage temperatures up to 21 days.
Anahtar Kelimeler
Pomegranate by-products | Nanophytosome | In vitro digestion | Nanoencapsulation