Effects of dietary marine sulphated polysaccharides (Algimun®) on growth performance, immune responses and disease resistance of juvenile gilthead seabream (Sparus aurata) to Photobacterium damselae subsp. piscicida
Yazarlar (11)
Prof. Dr. Derya GÜROY
Yalova Üniversitesi, Türkiye
Prof. Dr. Betül GÜROY
Yalova Üniversitesi, Türkiye
Soner Bilen
Kastamonu Üniversitesi, Türkiye
Ertuğrul Terzi
Kastamonu Üniversitesi, Türkiye
Osman Nezih Kenanoğlu
Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Serhan MANTOĞLU
Yalova Üniversitesi, Türkiye
Onur Karadal
İzmir Katip Çelebi Üniversitesi, Türkiye
Öğr. Gör. İzzet ŞAHİN
Yalova Üniversitesi, Türkiye
Halit Kuşku
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Fish & Shellfish Immunology (Q1) | ||
| Dergi ISSN | 1050-4648 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2022 |
| Cilt / Sayı / Sayfa | 127 / 0 / 1139–1147 | DOI | 10.1016/j.fsi.2022.07.054 |
| Makale Linki | https://doi.org/10.1016/j.fsi.2022.07.054 | ||
| Özet |
| The present study evaluated the effects of a dietary mix of marine sulphated polysaccharides, named Algimun® (AL), supplementation to gilthead seabream (Sparus aurata) juveniles in terms of growth performance, immune responses, and resistance against Photobacterium damselae subsp. piscicida. A total of 240 fish (initial mean weight of 6.00 ± 0.03 g) was randomly separated into 12 tanks (400 L, 20 fish per tank) distributed in four replicates. Fish were fed three experimental diets: a basal diet (Control), and a basal diet with two inclusion rates of Algimun® as 3 g/kg (AL0.3) and 5 g/kg (AL0.5) for 30 days before bacterial infection with P. damselae subsp. piscicida. After a 30-day feeding-period, growth performance was significantly improved in AL0.3 and AL0.5 groups compared to the control group (P < 0.05). AL0.3 and AL0.5 groups showed significantly higher lysozyme activity and myeloperoxidase activity when compared to the control group (P < 0.05). The gene expression of immune mediators (IL-1β, IL-6, IL-10, IL-18, TNF-α and COX-2) was significantly upregulated in the intestine, spleen and head kidney in AL0.3 and AL0.5 groups when compared to the control group (P < 0.05). Eight days post-challenge, the survival rate against P. damselae subsp. piscicida was numerically higher in fish within AL0.3 and AL0.5 groups compared to control (+20%). The study findings suggest that marine sulphated polysaccharides (Algimun®) could be used as an immunomodulator in gilthead seabream to support animal's health and boost resistance in case of disease outbreak. |
| Anahtar Kelimeler |
| Marine fish | Seaweed | Marine sulphate polysaccharide | Nutrition | Immunomodulation |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 8 |