Oral Valganciclovir As Preemptive Therapy for Cytomegalovirus Infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients
Yazarlar (9)
Vildan Özkocaman
Uludag University, Türkiye
Fahir Özkalemkaş
Uludag University, Türkiye
Rıdvan Ali
Uludag University, Türkiye
Dr. Öğr. Üyesi Yasemin KARACAN
Uludag University, Türkiye
Tuba Ersal
Uludag University, Türkiye
Hilmi Erdem Gözden
Türkiye
Esra Kazak
Türkiye
Emin Halis Akalın
Türkiye
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale) | ||
| Dergi Adı | Blood (Q1) | ||
| Dergi ISSN | 0006-4971 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2014 |
| Cilt / Sayı / Sayfa | 124 / 21 / 5855–0 | DOI | 10.1182/blood.V124.21.5855.5855 |
| Makale Linki | https://doi.org/10.1182/blood.v124.21.5855.5855 | ||
| Özet |
| Introduction: Cytomegalovirus (CMV) infection remains one of the most important complications after allogeneic hematopoietic stem cell transplantation (AlloHSCT). Preemptive therapy with oral VGC or intravenous ganciclovir has replaced universal prophylaxis. We investigated the effect of oral VGC as preemptive therapy on CMV reactivation or infection in AlloHSCT.Patient & Methods: We retrospectively studied 30 consecutive adult recipients of HLA-identical sibling allogeneic peripheral blood stem cell transplant from June 2011 through June 2014 to analyze the safety and efficacy of preemptive therapy for the treatment of CMV infection. Among 30 patients we studied the results of 13 patients with CMV DNA positivity. All 13 recipients and their donors were seropositive for CMV Ig G status. Their diagnosis of pretransplantation were as 8 acute myeloid leukemia (61 %) and 5 acute lymphocytic leukemia (39 … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 2 |
| Google Scholar | 2 |