Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic hematopoietic stem cell transplantation for acute leukemia patients: A single center experience
Yazarlar (1)
Dr. Öğr. Üyesi Yasemin KARACAN Yalova Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Transfusion and Apheresis Science (Q4) | ||
| Dergi ISSN | 1473-0502 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2013 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-12-2013 |
| Cilt / Sayı / Sayfa | 49 / 3 / 590–599 | DOI | 10.1016/j.transci.2013.07.030 |
| Makale Linki | https://doi.org/10.1016/j.transci.2013.07.030 | ||
| UAK Araştırma Alanları |
Dahili Hastalıklar Hemşireliği
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| Özet |
| Due to the high transplant related morbidity and mortality (TRM), relatively younger acute leukemia patients that have a good performance status and no comorbidity are eligible for myeloablative conditioning (MAC) followed by allogeneic hematopoietic stem cell transplantation (allo-HSCT).The outcomes of 84 consecutive adult patients with ALL (n = 38) or AML (n = 46) who underwent allo-HSCT from their HLA-identical siblings were evaluated retrospectively. The median age at transplantation was 34 (17–58 years) for the whole patient population. Of these, 24 patients received a MAC and 60 patients received a fludarabine-based reduced intensity conditioning regimen (RIC).After a median follow-up of 32 months (range, 1–119), for the entire group, the 3-year estimated overall survival (OS) was 57.5% and the disease-free survival (DFS) was 51.5%. The OS for ALL and AML patients were 53.9% vs 62.1%: and … |
| Anahtar Kelimeler |
| Allogeneic hematopoietic stem cell transplantation | Graft-versus-host disease | Myeloablative conditioning regimen | Reduced intensity conditioning regimen |
Science Direct
Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic hematopoietic stem cell transplantation for acute leukemia patients: A single center experience
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 9 |
| Scopus | 7 |
| Google Scholar | 16 |