Current Therapeutic Approaches in Infantile Colic: A Comprehensive Review
Yazarlar (7)
Vefik Arica
University of Health Sciences, Türkiye
University of Health Sciences, Türkiye
Emine Gözde Özdrama Yildiz
University of Health Sciences, Türkiye
University of Health Sciences, Türkiye
Sevilay Kök
University of Health Sciences, Türkiye
University of Health Sciences, Türkiye
Belen Ateş University of Health Sciences, Türkiye
Dr. Öğr. Üyesi Taner ADIGÜZEL Yalova Üniversitesi, Türkiye
Eren Güzeloğlu
University of Health Sciences, Türkiye
University of Health Sciences, Türkiye
Dr. Öğr. Üyesi Hüseyin Dağ University of Health Sciences, Türkiye
| Makale Türü |
Özgün Makale
(Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
|
||
| Dergi Adı | Turkish Archives of Pediatrics | ||
| Dergi ISSN | 2757-6256 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2025 |
| Cilt / Sayı / Sayfa | 61 / 6 / 463–470 | DOI | 10.5152/TurkArchPediatr.2025.25388 |
| Makale Linki | https://doi.org/10.5152/turkarchpediatr.2025.25388 | ||
| UAK Araştırma Alanları |
Çocuk Sağlığı ve Hastalıkları (Çocuk Sağlığı ve Hastalıkları)
|
||
| Özet |
| Objective: Infantile colic (IC) is a functional gastrointestinal disorder of early infancy defined by prolonged crying and irritability in otherwise healthy infants. This review synthesizes cur rent evidence on diagnosis and management, emphasizing feeding strategies, maternal diet, and the clinical relevance of lactose malabsorption with data from Türkiye and worldwide. The authors highlight strain‑specific probiotics: for breastfed infants, Lactobacillus reuteri DSM 17938 is associated with fewer crying minutes, whereas for bottle‑fed infants, the combination of Bifidobacterium breve BR03 and B. breve B632 shows preventive and symptomatic signals in randomized trials. Lactase enzyme can reduce symptoms when lactose malabsorption is suspected. Simethicone has not shown consistent benefit and is not recommended routinely. In light of the evolving evidence and inconsistent therapeutic outcomes, this review aims to sum marize current understanding and evidence‑based management strategies for IC.Materials and Methods: This narrative review was conducted through a comprehensive search of PubMed, Scopus, and Google Scholar databases for studies published between 2000 and 2025 using the keywords “infantile colic,”“functional gastrointestinal disorders,”“lactase,”“pro biotics,” and “maternal diet.” Relevant randomized controlled trials, meta‑analyses, and clinical guidelines were selected and synthesized to summarize current evidence.Results: Evidence suggests that targeted nutritional approaches, phenotype‑guided probiotic use, and maternal dietary adjustments provide measurable reductions in crying duration and caregiver … |
| Anahtar Kelimeler |
| Infantile colic | lactose intolerance | maternal diet | probiotics | simethicone |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 1 |
| Google Scholar | 5 |