Investigation of Antitumor Activity of Phycocyanin Obtained from Spirulina (Arthrospira) platensis in Mice
Yazarlar (5)
Doç. Dr. Sibel BAYIL OĞUZKAN Gaziantep Üniversitesi, Türkiye
İzzettin Güler Gaziantep Üniversitesi, Türkiye
Prof. Dr. Betül GÜROY Yalova Üniversitesi, Türkiye
Kemal Bakır Sanko Üniversitesi, Türkiye
Mehmet Özaslan Gaziantep Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı INTERNATIONAL JOURNAL OF PHARMACOLOGY (Q4)
Dergi ISSN 1811-7775 Dergi Bilgileri (2023)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 01-2023
Cilt / Sayı / Sayfa 19 / 1 / 114–121 DOI 10.3923/ijp.2023.114.121
Makale Linki http://dx.doi.org/10.3923/ijp.2023.114.121
UAK Araştırma Alanları
Su Ürünleri Yetiştiriciliği
Özet
Background and Objective Spirulina contains two types of biliproteins, i.e., C-phycocyanin and allophycocyanin. In this current in vivo study, phycocyanin’s antitumor impact was examined following its administration by gavage feeding to BALB/c mice with Ehrlich ascites tumor (EAT). Materials and Methods Phycocyanin was administered to three different experimental groups, treatment, control and prophylaxis in different concentrations and the antitumor activity in each group was detected in terms of a dosage effect. Statistical analyses were performed using SPSS 21 software, with the results expressed either as standard deviation or percentage. Results Total antioxidant level (TAL) of the prophylaxis group was found to be statistically significant compared with the control group. When the prophylaxis groups were statistically compared with each other, a significant increase was observed in the values as the dose …
Anahtar Kelimeler
Phycocyanin | Ehrlich ascites tumour | phytotherapy | antitumor
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 1
Investigation of Antitumor Activity of Phycocyanin Obtained from Spirulina (Arthrospira) platensis in Mice