Effect of subchorionic hematoma on first-trimester maternal serum free (3-hCG and PAPP-A levels
Yazarlar (7)
Dr. Öğr. Üyesi Arife AKAY ACEMOĞLU Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
Yildiz Akdas Reis Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
Busra Sahin Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
Asya Kalayci Oncu Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
Mehmet Obut Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
Cantekin Iskender Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
Sevki Celen Etlik Zubeyde Hanim Gynecology Education & Research Hospital, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Revista Brasileira De Ginecologia E Obstetricia | ||
| Dergi ISSN | 0100-7203 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2024 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-01-2024 |
| Cilt / Sayı / Sayfa | 46 / 1 / – | DOI | 10.61622/rbgo/2024rbgo66 |
| Makale Linki | https://doi.org/10.61622/rbgo/2024rbgo66 | ||
| UAK Araştırma Alanları |
Kadın Hastalıkları ve Doğum
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| Özet |
| Objective: This study aimed to investigate the effects of the presence of subchorionic hematoma (SH) in early pregnancies with threatened miscarriage (TM) on levels of first-trimester maternal serum markers, pregnancy-associated plasma protein-A (PAPP-A), and free β-human chorionic gonadotropin (β-hCG) levels. Methods: The data of TM cases with SH in the first trimester between 2015 and 2021 were evaluated retrospectively. The data of age and gestational age-matched TM cases without SH were also assessed to constitute a control group. Demographic characteristics, obstetric histories, ultrasonographic findings, and free β-hCG and PAPP-A levels of the groups were compared. Results: There were 119 cases in the study group and 153 cases in the control group. The median vertical and longitudinal lengths of the SH were 31 mm and 16 mm. The median age of both groups was similar (p=0.422). The MoM value of PAPP-A was 0.088 (.93) in the study group and 0.9 (0.63) in the control group (p=0.519). Similarly, the MoM value of free β-hCG was 1.04 (0.78) in the study group and 0.99 (0.86) in the control group (p=0.66). No significant relationship was found in the multivariate analysis between free β-hCG MoM, PAPP-A MoM, age, gravida, and vertical and longitudinal lengths of the hematoma (p>0.05). Conclusion: The level of PAPP-A and free β-hCG were not affected by the SH. Therefore, these markers can be used reliably in TM cases with SH for the first-trimester fetal aneuploidy screening test. |
| Anahtar Kelimeler |
| "Abortion | threatened" | "Chorionic gonadotropin" | "Subchorionichematoma" | "Pregnancy-associated plasma protein-A" | "Pregnancy trimester first" | "Aneuploidy" | "Biomarkers" |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 1 |
| PubMed | 1 |