Isolated polyhydramnios in the third trimester or polyhydramnios secondary to late-onset gestational diabetes: is it worth distinguishing?
Yazarlar (8)
Sadullah Ozkan Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Murat Levent Dereli Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Sadun Sucu Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Erol Nadi Varli Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Dr. Öğr. Üyesi Arife AKAY ACEMOĞLU Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Safiye Elif Uzlu Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Ali Turhan Caglar Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Yaprak Engin-Ustun Etlik Lady Zubeyde Matern & Womens Hlth Teaching &, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Revista Da Associacao Medica Brasileira (Q2)
Dergi ISSN 0104-4230 Dergi Bilgileri (2024)
Dergi Tarandığı Indeksler SCI
Makale Dili Türkçe Basım Tarihi 01-2024
Kabul Tarihi – Yayınlanma Tarihi 01-01-2024
Cilt / Sayı / Sayfa 70 / 6 / – DOI 10.1590/1806-9282.20231390
Makale Linki https://doi.org/10.1590/1806-9282.20231390
UAK Araştırma Alanları
Kadın Hastalıkları ve Doğum
Özet
OBJECTIVE: The aim of this study was to compare pregnancy outcomes of patients with polyhydramnios due to late-onset gestational diabetes mellitus and patients with isolated polyhydramnios. METHODS: Of the women who fully participated in prenatal examinations at Etlik Lady Zübeyde Hospital between January 1, 2018, and December 31, 2019, women with polyhydramnios of nonfetal–placental origin manifesting in the third trimester were retrospectively reviewed. Women with normal 75-g oral glucose tolerance test results between 24 and 28 weeks gestation who met the inclusion criteria were enrolled in the study and divided into two groups based on the results of rescreening with the 75-g oral glucose tolerance test for polyhydramnios in the third trimester: women with isolated polyhydramnios (group 1) and women with late-onset polyhydramnios due to gestational diabetes mellitus (group 2). RESULTS: There were a total of 295 participants, of whom 35 (11.8%) were diagnosed with polyhydramnios due to late-onset gestational diabetes mellitus. There were no differences in the main outcomes. Birthweight and gestational age at birth were identified as independent risk factors for predicting composite maternal outcome {[odds ratio (OR)=1.273, 95% confidence interval (CI) 1.063–1.524, p=0.009]} and composite neonatal outcome (OR=0.606, CI 0.494–0.744, p<0.001), respectively. CONCLUSION: Polyhydramnios in late pregnancy without evidence of pregnancy-related causes leading to polyhydramnios may be a sign of late-onset gestational diabetes mellitus in women with a normal prior oral glucose tolerance test. As pregnancy outcomes and management were indifferent, it does not seem necessary or useful to diagnose whether or not late-onset gestational diabetes mellitus is present.
Anahtar Kelimeler
"Gestational diabetes mellitus" | "Polyhydramnios" | "Late-onset" | "Outcome" | "Oral glucose tolerance test"