Does the presence of extended jugular lymphatic sacs add more risk to nuchal thickness for genetic and structural abnormality?
Yazarlar (9)
Mehmet Obut Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Dr. Öğr. Üyesi Arife AKAY ACEMOĞLU Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Ibanoglu Müjde Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Özge Çelik Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Asya Öncü Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Dr. Öğr. Üyesi Zuat Acar Sisli Hamidiye Etfal Training And Research Hospital, Türkiye
Erdal Seker
Ankara Üniversitesi, Türkiye
Erkan Saglam Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Cantekin Iskender Etlik Zubeyde Hanim Women's Health Training And Research Hospital, Türkiye
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Medical Ultrasound
Dergi ISSN 0929-6441 Dergi Bilgileri (2023)
Dergi Tarandığı Indeksler ESCI
Makale Dili Türkçe Basım Tarihi 04-2023
Kabul Tarihi 05-07-2022 Yayınlanma Tarihi 09-11-2022
Cilt / Sayı / Sayfa 31 / 2 / 119–126 DOI 10.4103/jmu.jmu_225_21
Makale Linki https://doi.org/10.4103/jmu.jmu_225_21
UAK Araştırma Alanları
Kadın Hastalıkları ve Doğum
Özet
Background: The risks added by extended jugular lymphatic sacs (EJLS) to increased nuchal translucency (NT) including genetic and structural abnormalities and pregnancy outcomes have not been previously investigated, which this study aims to investigate. Methods: The data of 155 singleton pregnancies with increased fetal NT (≥95 th percentile) of these 20 with fetal EJLS were evaluated retrospectively. Patients were stratified according to NT thickness such that ≥95 th percentile - 3.5 mm, 3.6-4.4 mm, 4.5-5.4 mm, 5.5-6.4 mm, ≥6.5 mm, and grouped according to the presence of EJLS. Pregnancy outcomes, genetic and structural abnormalities were assessed by comparing EJLS with non-EJSL cases (n-EJLS). Results: Associated with NT, the incidence of the presence of EJLS increased with NT, from 4.5% at the ≥95 th percentile - 3.5 mm to 30.8% when NT ≥5.5 mm. In the n-EJLS group, the proportion of fetuses with structural and genetic abnormalities increased as the measurement of NT increased. This correlation was not observed in the EJLS group. Compared to n-EJLS, cases with EJLS had a higher rate of fetal structural (38.5% vs. 75%, P = 0.003) and genetic (18.5% vs. 45%, P = 0.005) anomalies and a lower term live birth rate (59.3% vs. 15%, P < 0.001). Conclusion: The increasing rate of EJLS was seen as NT increased. Compared to n-EJLS, the EJLS cases had a higher rate poor pregnancy outcomes and fetal genetic and structural abnormalities.
Anahtar Kelimeler
"Abnormal karyotype" | "cystic hygroma" | "jugular lymphatic sac" | "nuchal thickness" | "structural abnormality"