Increased Neutrophil to Lymphocyte and Platelet of Lymphocyte Ratios in Patients with First Episode Psychosis
Yazarlar (5)
Doç. Dr. Musa ŞAHPOLAT Kilis State Hospital, Türkiye
Mehmet Akif Karaman American University of the Middle East, Kuveyt
Doç. Dr. Ebru Ozturk Copur Kilis 7 Aralik Univ Yusuf Serefoglu, Türkiye
Duygu Ayar Kilis 7 Aralik Univ Yusuf Serefoglu, Türkiye
Cem Sesliokuyucu Hatay Iskenderun State Hospital, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | MEDICAL JOURNAL OF BAKIRKOY | ||
| Dergi ISSN | 1305-9319 Dergi Bilgileri (2022) | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2022 |
| Cilt / Sayı / Sayfa | 18 / 1 / 59–64 | DOI | 10.4274/BMJ.galenos.2022.2021.11-9 |
| UAK Araştırma Alanları |
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| Özet |
| Objective: Inflammatory processes have a main role in the etiopathogenesis of psychosis. The aim of current study was to examine differences between the patients with the first episode psychosis's (FEPP) neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) levels with the healthy control groups The NLR and PLR are indicators that may define the existence of systemic inflammatory response. Methods: The participants of this study included 37 FEPP and 43 healthy individuals who had similar socio-demographic characteristics compared to the patient group. The Positive and Negative Syndrome Scale was conducted to collect data from the patient group. Additionally, participants' complete blood count parameters were analyzed for the study. Results: The mean NLR and PLR levels of FEPP were significantly higher than the healthy control individuals (p=0.001 and p=0.045). There was no relationship between demographic variables, body mass index, smoking, severity of disease and NLR-PLR. Conclusion: Based on the literature review and electronic database search, no previous study evaluated PLR in the context of FEP. Therefore, the current study was first examining both NLR and PLR levels in FEP as hematologic inflammatory indicators. Our results indicated that inflammatory processes may play a role in the etiopathogenesis of psychosis. |
| Anahtar Kelimeler |
| The first episode psychosis | inflammation | lymphocyte | neutrophil |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 3 |