Development of ultra-sensitive and selective molecularly imprinted polymer-based electrochemical sensor for L-lactate detection
Yazarlar (8)
Ensar Piskin
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
Prof. Dr. Ahmet Cetinkaya Ankara Üniversitesi, Türkiye
Zülal Eryaman
Yalova Üniversitesi, Türkiye
Yalova Üniversitesi, Türkiye
Leyla Karadurmus
Adiyaman Üniversitesi, Türkiye
Adiyaman Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mehmet Altay Unal Ankara Üniversitesi, Türkiye
Prof. Dr. Mustafa Kemal Sezgintürk Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Prof. Dr. Fehime Jülide HIZAL YÜCESOY Yalova Üniversitesi, Türkiye
Sibel A. Ozkan
Ankara Üniversitesi, Türkiye
Ankara Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Microchemical Journal (Q1) | ||
| Dergi ISSN | 0026-265X Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2024 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-09-2024 |
| Cilt / Sayı / Sayfa | 204 / 1 / – | DOI | 10.1016/j.microc.2024.111163 |
| Makale Linki | http://dx.doi.org/10.1016/j.microc.2024.111163 | ||
| UAK Araştırma Alanları |
Analitik Kimya
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| Özet |
| Lactate detection is important for the food and healthcare industries, and it's especially important when there's tissue hypoxia, hepatic illness, bleeding, respiratory failure, or sepsis. A new molecularly imprinted polymer (MIP) based electrochemical sensor was fabricated for differential pulse voltammetric assay of L-lactate (LAC). By using ZIF-8@ZnQ nanoparticles, the number of regions and effective surface area were increased. The polymeric film was obtained using 4 aminobenzoic acid (4-ABA) as a functional monomer, ethylene glycol dimethacrylate (EGDMA) as a cross-linker, 2-hydroxyethyl methacrylate (HEMA) as basic monomers, and 2-hydroxy-2-methylpropiophenone one as initiator. The developed 4-ABA/LAC/ZIF-8@ZnQ@MIP-GCE was morphologically characterised using SEM and electrochemically using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) measurements. A linear range of 0.1–1.0 pM LAC with a detection limit of 29.9 fM was found. Lastly, the MIP-based electrochemical sensor detected LAC in commercial human serum samples. |
| Anahtar Kelimeler |
| L-lactate | Molecularly imprinted polymers | Nanoparticle | Photopolymerization | Voltammetry |
Science Direct
Development of ultra-sensitive and selective molecularly imprinted polymer-based electrochemical sensor for L-lactate detection
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Yöksis | 16 |
| Web of Science | 32 |
| Scopus | 36 |