Rapid synthesis of polyester based single-chain polymeric nanoparticles via an intra-molecular aza-Michael addition reaction
Yazarlar (4)
Öğr. Gör. Dr. Burcu ALKAN
Yalova Üniversitesi, Türkiye
Özgün Dağlar
Türkiye
Hakan Durmaz
Türkiye
Prof. Dr. İsmail Gökhan TEMEL
Yalova Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Polymer Chemistry (Q1) | ||
| Dergi ISSN | 1759-9954 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2022 |
| Cilt / Sayı / Sayfa | 13 / 0 / 2442–2449 | DOI | 10.1039/D1PY01631H |
| Makale Linki | http://dx.doi.org/10.1039/d1py01631h | ||
| Özet |
| An alternative strategy was developed to prepare intramolecularly crosslinked soft nanoparticles using the aza-Michael addition reaction of a linear polyester (PCA) containing in-chain reactive triple bonds. The linear precursor was achieved using the conventional polyesterification method in the presence of an acid catalyst. Single-chain polymeric nanoparticles were successfully synthesized by the aza-Michael addition route using a bifunctional amine compound and PCA in a short reaction period (15 min). The resulting polymeric nanoparticles exhibited lower hydrodynamic radii compared to their linear analogues (Rh < 5.55 nm). Crosslinked particles transformed into globular morphologies due to the collapse process as well. Additionally, the achieved nanoparticles were exploited for post-modifications via a thiol-Michael addition reaction. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 14 |