Preparation of collagen modified photopolymers a new type of biodegradable gel for cell growth
Yazarlar (6)
Doç. Dr. Gülay BAYRAMOĞLU Yalova Üniversitesi, Türkiye
Nilhan Kayaman-Apohan
Marmara Üniversitesi, Türkiye
Marmara Üniversitesi, Türkiye
Prof. Dr. Handan Akçakaya İstanbul Tıp Fakültesi, Türkiye
Prof. Dr. Memet Vezir Kahraman Marmara Üniversitesi, Türkiye
Serap Erdem Kuruca
İstanbul Tıp Fakültesi, Türkiye
İstanbul Tıp Fakültesi, Türkiye
Atilla Güngör
Marmara Üniversitesi, Türkiye
Marmara Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Materials Science Materials in Medicine (Q2) | ||
| Dergi ISSN | 0957-4530 Dergi Bilgileri (2010) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2010 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 20-11-2009 |
| Cilt / Sayı / Sayfa | 21 / 2 / 761–775 | DOI | 10.1007/s10856-009-3929-4 |
| Makale Linki | http://link.springer.com/10.1007/s10856-009-3929-4 | ||
| UAK Araştırma Alanları |
Polimer Bilimi
|
||
| Özet |
| In this study a new branched methacrylated poly(propylene glycol-co-lactic acid) (PPG–PLA–IEM) and methacrylated cellulose acetate butyrate resin (CAB–IEM) were synthesized. Hydrogels with various amounts of PPG–PLA–IEM and CAB–IEM (25, 50 and 75 wt% IEM modified) were prepared by photopolymerization. Collagen tethered PEG–monoacrylate (PEGMA–collagen) was prepared and introduced as a bioactive moiety to modify the hydrogel in order to enhance cell affinity. In vitro attachment and growth of 3T3 mouse fibroblasts and human umbilical vein endothelial cells (HUVEC) on the hydrogels with and without collagen were also investigated. It was observed that, the collagen improves the cell adhesion onto the hydrogel surface. With the increasing amount of collagen, cell viability increased by 28% for ECV304 (P < 0.05) and 30% for 3T3 (P < 0.05). |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 16 |
| Scopus | 17 |
| Google Scholar | 20 |